Synthesis of {3-(2-dimethylamino-ethy1)-2-[3-(2- dimethylaminoethyl)-1H-indol-5-ylmethyl]-1H-indol-5-yl}-N- methyl-methanesulfonamide, the main Sumatriptan impurity

نویسندگان

  • A. Sanz
  • A. M. G. Carril
  • M. P. Matía
  • J. L. Novella
  • J. Alvarez-Builla
چکیده

An improved multistep synthesis of {3-(2-dimethylamino-ethy1)-2-[3-(2dimethylaminoethyl)-1H-indol-5-ylmethyl]-1H-indol-5-yl}-N-methyl-methanesulfonamide, the main Sumatriptan impurity, is described, as a model for other related triptan derivatives.

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تاریخ انتشار 2007